E3 Ligase Ligand-linker Conjugate 174,E3 Ligase Ligand-linker Conjugate 176 Suppliers & Manufacturers

IUPAC Name: N-(8-aminooctyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid | CAS Registry Number: 1950635-16-1
Synonyms: E3 ligase Ligand-Linker Conjugates 17, SCHEMBL17839806, CS-7756, HY-103614

Molecular Formula:	C₂₅H₃₁F₃N₄O₈	Molecular Weight:	572.538 [g/mol]
H-Bond Donor:	4	H-Bond Acceptor:	12

InChIKey: AJVLNIUPDHKOPS-UHFFFAOYSA-N

1950635-16-1

E3 ubiquitin ligase binder-1 (1 supplier)

IUPAC Name: 1-(4-piperidin-4-ylphenyl)-1,3-diazinane-2,4-dione;hydrochloride | CAS Registry Number: 2446913-99-9
Synonyms: 1-[4-(piperidin-4-yl)phenyl]-1,3-diazinane-2,4-dionehydrochloride, SCHEMBL22119523, HY-W595340, DA-63085, CS-0652603, 1-[4-(4-piperidyl)phenyl]hexahydropyrimidine-2,4-dione;hydrochloride

Molecular Formula:	C₁₅H₂₀ClN₃O₂	Molecular Weight:	309.790 [g/mol]
H-Bond Donor:	3	H-Bond Acceptor:	3

InChIKey: LMDRQYPOPFBGMY-UHFFFAOYSA-N

2446913-99-9

E3,Z8,Z11-Tetradecatriene acetate (12 suppliers)

IUPAC Name: tetradeca-1,3,5-trienyl acetate | CAS Registry Number: 163041-94-9
Synonyms: Acetic acid tetradeca-3,8,11-trienyl ester, (3E,8Z,11Z)-TETRADECATRIENYL ACETATE

Molecular Formula:	C₁₆H₂₆O₂	Molecular Weight:	250.376440 [g/mol]
H-Bond Donor:	0	H-Bond Acceptor:	2

InChIKey: DMPBOULTBKYSQE-UHFFFAOYSA-N

163041-94-9

E3330 (8 suppliers)

IUPAC Name: (2E)-2-[(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)methylidene]undecanoic acid | CAS Registry Number: 136164-66-4
Synonyms: E 3330, E-3330, AC1O5RL8, SureCN3758716, CHEMBL578390, CHEBI:681852, (2E)-3-(5-(2,3-Dimethoxy-6-methyl-1,4-benzoquinoyl))-2-nonyl-2-propenoic acid, (2E)-2-[(4,5-Dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)methylene]-undecanoic acid, (2E)-2-[(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)methylidene]undecanoic acid, Undecanoic acid, 2-((4,5-dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)methylene)-, (E)-

Molecular Formula:	C₂₁H₃₀O₆	Molecular Weight:	378.459300 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	6

InChIKey: AALSSIXXBDPENJ-FYWRMAATSA-N

136164-66-4

E3P13 (1 supplier)

459853-10-2

E4 PROTEIN,TOMATO (3 suppliers)

127362-11-2

E4,6-Dichloro-5-fluoronicotinic acid (8 suppliers)

IUPAC Name: 4,6-dichloro-5-fluoropyridine-3-carboxylic acid | CAS Registry Number: 154012-18-7
Synonyms: 3-Pyridinecarboxylic acid, 4,6-dichloro-5-fluoro-, ACMC-20n6vm, CTK0B1070

Molecular Formula:	C₆H₂Cl₂FNO₂	Molecular Weight:	209.989983 [g/mol]
H-Bond Donor:	1	H-Bond Acceptor:	4

InChIKey: UYTWCEYZEQBILY-UHFFFAOYSA-N

154012-18-7

E55888 (1 supplier)

IUPAC Name: N,N-dimethyl-2-[3-(1,3,5-trimethylpyrazol-4-yl)phenyl]ethanamine | CAS Registry Number: 1034142-33-0
Synonyms: CHEMBL4205349, N,N-dimethyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)phenethylamine, E-55888, E 55888, GTPL3929, SCHEMBL3337502, TQP0823, BDBM50458526, Q27077141, N,N-dimethyl-2-[3-(1,3,5-trimethylpyrazol-4-yl)phenyl]ethanamine, dimethyl-{2-[3-(1,3,5-trimethyl-1H-pyrazol-4-yl)-phenyl]-ethyl}-amine, dimethyl-{2-[3-(1,3,5-trimethyl-1h-pyrazol-4-yl)-phenyl]ethyl}-amine, N,N-dimethyl-2-(3-(1,3,5-trimethyl-1H-pyrazol-4-yl)phenyl)ethanamine, N,?N-?dimethyl-?3-?(1,?3,?5-?trimethyl-?1H-?pyrazol-?4-?yl)?phenethylamine

Molecular Formula:	C₁₆H₂₃N₃	Molecular Weight:	257.370 [g/mol]
H-Bond Donor:	0	H-Bond Acceptor:	2

InChIKey: MFUWRMRKXKCSPL-UHFFFAOYSA-N

1034142-33-0

E5700 (1 supplier)

750597-23-0

E6 BERBAMINE (5 suppliers)

Synonyms: NSC147754, CID287690

Molecular Formula:	C₃₉H₄₂N₂O₇	Molecular Weight:	650.759980 [g/mol]
H-Bond Donor:	0	H-Bond Acceptor:	9

InChIKey: QQHBFLLFMBTZBU-UHFFFAOYSA-N

73885-53-7

E6-272 (2 suppliers)

945142-65-4

E6130 (3 suppliers)

IUPAC Name: 2-[(3S,4R)-1-[[2-chloro-6-(trifluoromethyl)phenyl]methyl]-3-[[1-(cyclohexen-1-ylmethyl)piperidin-4-yl]carbamoyl]-4-methylpyrrolidin-3-yl]acetic acid | CAS Registry Number: 1427058-33-0
Synonyms: CHEMBL4518556, 2-[(3S,4R)-1-[[2-chloro-6-(trifluoromethyl)phenyl]methyl]-3-[[1-(cyclohexen-1-ylmethyl)piperidin-4-yl]carbamoyl]-4-methylpyrrolidin-3-yl]acetic acid, SCHEMBL14760920, CHC05833, HY-107456, CS-0028524, 2-[(3S,4R)-1-{[2-Chloro-6-(trifluoromethyl)phenyl]methyl}-3-{[1-(cyclohex-1-en-1-ylmethyl) piperidin-4-yl]carbamoyl}-4-methylpyrrolidin-3-yl]acetic acid

Molecular Formula:	C₂₈H₃₇ClF₃N₃O₃	Molecular Weight:	556.100 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	8

InChIKey: JTJKDYLEMNXXER-UZTOHYMASA-N

1427058-33-0

E6201 (2 suppliers)

IUPAC Name: (2E,5S,6S,8Z,10R,11S)-17-(ethylamino)-5,6,15-trihydroxy-10,11-dimethyl-12-oxabicyclo[12.4.0]octadeca-1(18),2,8,14,16-pentaene-7,13-dione | CAS Registry Number: 603987-35-5
Synonyms: UNII-CZP9GB25HO, SureCN6983345, CHEMBL1097999, RL04278, ER 806201, E 6201, E-6201, (3S,4R,5Z,8S,9S,11E)-14-(Ethylamino)-8, 9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione, 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 14-(ethylamino)-3,4,9,10-tetrahydro-8,9,16-trihydroxy-3,4-dimethyl-, (3S,4R,5Z,8S,9S,11E)-, 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 14-(ethylamino)-3,4,9,10-tetrahydro-8,9,16-trihydroxy-3,4-dimethyl-, (3S,4R,5Z,8S,9S,11E)-

Molecular Formula:	C₂₁H₂₇NO₆	Molecular Weight:	389.442180 [g/mol]
H-Bond Donor:	4	H-Bond Acceptor:	7

InChIKey: MWUFVYLAWAXDHQ-HMNLTAHHSA-N

603987-35-5

E6446 (7 suppliers)

IUPAC Name: 6-(3-pyrrolidin-1-ylpropoxy)-2-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-1,3-benzoxazole | CAS Registry Number: 1219925-73-1
Synonyms: SCHEMBL12396763, ZINC68203163, AKOS030526329, CS-3967, HY-12756, 6-(3-Pyrrolizinopropoxy)-2-[4-(3-pyrrolizinopropoxy)phenyl]benzoxazole, 6-(3-(pyrrolidin-1-yl)propoxy)-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)benzo[d]oxazole

Molecular Formula:	C₂₇H₃₅N₃O₃	Molecular Weight:	449.595 [g/mol]
H-Bond Donor:	0	H-Bond Acceptor:	6

InChIKey: YMYJXFUPMPMETB-UHFFFAOYSA-N

1219925-73-1

E6446 dihydrochloride (6 suppliers)

IUPAC Name: 6-(3-pyrrolidin-1-ylpropoxy)-2-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-1,3-benzoxazole;dihydrochloride | CAS Registry Number: 1345675-25-3
Synonyms: E6446 (dihydrochloride), E-6446 Dihydrochloride, MolPort-044-831-694, BCP29147, HY-12756A, AKOS030526425, CS-4521, AK547246, E6446 HCl; E6446; E-6446; E6446 hydrochloride

Molecular Formula:	C₂₇H₃₇Cl₂N₃O₃	Molecular Weight:	522.511 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	6

InChIKey: DQOUZINBHKWGGM-UHFFFAOYSA-N

1345675-25-3

E64FC26 (5 suppliers)

IUPAC Name: (1E)-1-nonylidene-3-(trifluoromethyl)indene-5,6-diol | CAS Registry Number: 2285446-62-8
Synonyms: (E/Z)-E64FC26, CHEMBL4751979, SCHEMBL21100897, 2285446-67-3, BDBM50550835, HY-122895A, (1E)-1-nonylidene-3-(trifluoromethyl)indene-5,6-diol, (E)-1-Nonylidene-3-(trifluoromethyl)-1H-indene-5,6-diol

Molecular Formula:	C₁₉H₂₃F₃O₂	Molecular Weight:	340.400 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	5

InChIKey: OWYMWLCFHDHVAH-UKTHLTGXSA-N

2285446-62-8

E67-2 (2 suppliers)

IUPAC Name: 7-(5-aminopentoxy)-2-N-[3-(dimethylamino)propyl]-6-methoxy-4-N,4-N-dimethylquinazoline-2,4-diamine | CAS Registry Number: 1364914-62-4
Synonyms: SCHEMBL14952549, HY-122746, CS-0088648, 7-((5-Aminopentyl)oxy)-N2-(3-(dimethylamino)propyl)-6-methoxy-N4,N4-dimethylquinazoline-2,4-diamine, N-[3-(Dimethylamino)propyl]-N',N'-dimethyl-6-methoxy-7-(5-aminopentyloxy)quinazoline-2,4-diamine

Molecular Formula:	C₂₁H₃₆N₆O₂	Molecular Weight:	404.500 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	8

InChIKey: WLFIYSGBVULZIU-UHFFFAOYSA-N

1364914-62-4

E6801 (2 suppliers)

IUPAC Name: 6-chloro-N-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]imidazo[2,1-b][1,3]thiazole-5-sulfonamide | CAS Registry Number: 528859-04-3
Synonyms: E-6801, UNII-W4Q1543X33, CHEMBL362628, W4Q1543X33, 6-chloro-N-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]imidazo[2,3-b][1,3]thiazole-5-sulfonamide, N-(3-(2-Dimethylaminoethyl)-1H-indol-5-yl)-6-chloroimidazo(2,1-b)thiazole-5-sulfonamide, E 6801, GTPL3217, SCHEMBL1028804, BDBM34152, Imidazo(2,1-b)thiazole-5-sulfonamide, 6-chloro-N-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-, Q487086, 6-chloro-n-(3-(2-(dimethylamino)ethyl)-1h-indol-5-yl)imidazo[2,1-b]thiazole-5-sulfonamide, 6-chloro-N-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]imidazo[2,1-b][1,3]thiazole-5-sulfonamide

Molecular Formula:	C₁₇H₁₈ClN₅O₂S₂	Molecular Weight:	423.900 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	6

InChIKey: RZAXUKVIIWUIOM-UHFFFAOYSA-N

528859-04-3

E7016 (5 suppliers)

Synonyms: UNII-M8926C7ILX, E-7016, SureCN1319757, M8926C7ILX, GPI-21016, US8470825, 16, Benzopyrano(4,3,2-de)phthalazin-3(2H)-one, 10-((4-hydroxy-1-piperidinyl)methyl)-

Molecular Formula:	C₂₀H₁₉N₃O₃	Molecular Weight:	349.383160 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	5

InChIKey: HAVFFEMDLROBGI-UHFFFAOYSA-N

902128-92-1

E7046 (6 suppliers)

IUPAC Name: 4-[(1S)-1-[[3-(difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]pyrazole-4-carbonyl]amino]ethyl]benzoic acid | CAS Registry Number: 1369489-71-3
Synonyms: UNII-YWY620GU8I, YWY620GU8I, ER-886046, E-7046, MKLKAQMPKHNQPR-NSHDSACASA-N, SCHEMBL881212, CHEMBL3670685, MolPort-044-561-624, BDBM119448, ZINC114766778, CS-7559, Benzoic acid, 4-((1S)-1-(((3-(difluoromethyl)-1-methyl-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazol-4-yl)carbonyl)amino)ethyl)-, HY-103088, US8686018, 107, (S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazole-4-carboxamido)ethyl)benzoic acid, 4-[(1S)-1-[[3-(difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]pyrazole-4-carbonyl]amino]ethyl]benzoic acid

Molecular Formula:	C₂₂H₁₈F₅N₃O₄	Molecular Weight:	483.395 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	10

InChIKey: MKLKAQMPKHNQPR-NSHDSACASA-N

1369489-71-3

E7080 (3 suppliers)

17716-92-8

E7090 (4 suppliers)

IUPAC Name: 5-[2-[[4-[1-(2-hydroxyethyl)piperidin-4-yl]benzoyl]amino]pyridin-4-yl]oxy-6-(2-methoxyethoxy)-N-methylindole-1-carboxamide | CAS Registry Number: 1622204-21-0
Synonyms: E-7090, tasurgratinib, TN7CUD1NGA, UNII-TN7CUD1NGA, 5-((2-(4-(1-(2-hydroxyethyl)piperidin-4-yl)benzamido)pyridin-4-yl)oxy)-6-(2-methoxyethoxy)-N-methyl-1H-indole-1-carboxamide, 5-[2-[[4-[1-(2-hydroxyethyl)piperidin-4-yl]benzoyl]amino]pyridin-4-yl]oxy-6-(2-methoxyethoxy)-N-methylindole-1-carboxamide, CHEMBL3686884, SCHEMBL15955142, GTPL11414, BDBM142256, Fgf/fgfr pathway inhibitor E7090, BCP29727, EX-A2908, NSC806388, NSC-806388, SB18854, Example 22 [WO2014129477A1], HY-101466, CS-0021430, E 7090; E7090

Molecular Formula:	C₃₂H₃₇N₅O₆	Molecular Weight:	587.700 [g/mol]
H-Bond Donor:	3	H-Bond Acceptor:	8

InChIKey: IBHOLSBDZMIPPT-UHFFFAOYSA-N

1622204-21-0

E7090 (succinate) (4 suppliers)

IUPAC Name: butanedioic acid;5-[2-[[4-[1-(2-hydroxyethyl)piperidin-4-yl]benzoyl]amino]pyridin-4-yl]oxy-6-(2-methoxyethoxy)-N-methylindole-1-carboxamide | CAS Registry Number: 1879965-80-6
Synonyms: UNII-YRZ52NF9Y4, YRZ52NF9Y4, butanedioic acid;5-[2-[[4-[1-(2-hydroxyethyl)piperidin-4-yl]benzoyl]amino]pyridin-4-yl]oxy-6-(2-methoxyethoxy)-N-methylindole-1-carboxamide, Tasurgratinib succinate, SCHEMBL19019799, 5-((2-(((4-(1-(2-Hydroxyethyl)piperidin-4-yl)phenyl)carbonyl)amino)pyridin-4-yl)oxy)-6-(2-methoxyethoxy)-N-methyl-1H-indole-1-carboxamidesuccinate (1:1.5), Butanedioic acid, compd. with 5-((2-((4-(1-(2-hydroxyethyl)-4-piperidinyl)benzoyl)amino)-4-pyridinyl)oxy)-6-(2-methoxyethoxy)-N-methyl-1H-indole-1-carboxamide (3:2)

Molecular Formula:	C₃₆H₄₃N₅O₁₀	Molecular Weight:	705.800 [g/mol]
H-Bond Donor:	5	H-Bond Acceptor:	12

InChIKey: DLFIYSXIMACKCX-UHFFFAOYSA-N

1879965-80-6

E7107 (1 supplier)

IUPAC Name: [(2S,3S,4E,6S,7R,10R)-7,10-dihydroxy-2-[(2E,4E,6R)-6-hydroxy-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-3,7-dimethyl-12-oxo-1-oxacyclododec-4-en-6-yl] 4-cycloheptylpiperazine-1-carboxylate | CAS Registry Number: 630100-90-2
Synonyms: UNII-R60DZX1E2N, SureCN3624011, R60DZX1E2N, SCHEMBL3624011, E 7107, (3R,6R,7S,8E,10S,11S,12E,14E,16R,18R,19R,20R,21S)-7-[(4-cycloheptylpiperazin-1-yl)carbonyl]oxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoyxtrichosa-8,12,14-trien-11-olide, 1-Piperazinecarboxylic acid, 4-cycloheptyl-, (2S,3S,4E,6S,7R,10R)-7,10-dihydroxy-2-((1E,3E,5R)-5-hydroxy-6-((2R,3R)-3-((1R,2S)-2-hydroxy-1-methylbutyl)oxiranyl)-1,5-dimethyl-1,3-hexadienyl)-3,7-dimethyl-12-oxooxacyclododec-4-en-6-yl ester

Molecular Formula:	C₄₀H₆₆N₂O₉	Molecular Weight:	718.960040 [g/mol]
H-Bond Donor:	4	H-Bond Acceptor:	10

InChIKey: MNOMBFWMICHMKG-MGYWSNOQSA-N

630100-90-2

E722-2648 (1 supplier)

931963-55-2

E7449 (7 suppliers)

Synonyms: UNII-9X5A2QIA7C, 9X5A2QIA7C, SCHEMBL3886731, HY-12418, E-7449, 3H-Pyridazino(3,4,5-de)quinazolin-3-one, 8-((1,3-dihydro-2H-isoindol-2-yl)methyl)-1,2-dihydro-

Molecular Formula:	C₁₈H₁₅N₅O	Molecular Weight:	317.344600 [g/mol]
H-Bond Donor:	2	H-Bond Acceptor:	5

InChIKey: JLFSBHQQXIAQEC-UHFFFAOYSA-N

1140964-99-3

E7449 mesylate (1 supplier)

IUPAC Name: 11-(1,3-dihydroisoindol-2-ylmethyl)-2,3,10,12-tetrazatricyclo[7.3.1.05,13]trideca-1,5(13),6,8,11-pentaen-4-one;methanesulfonic acid | CAS Registry Number: 1140965-47-4
Synonyms: 8-(Isoindolin-2-ylmethyl)-2H-pyridazino[3,4,5-de]quinazolin-3(9H)-one methanesulfonate

Molecular Formula:	C₁₉H₁₉N₅O₄S	Molecular Weight:	413.500 [g/mol]
H-Bond Donor:	3	H-Bond Acceptor:	6

InChIKey: SQQZCNVWIZVPBE-UHFFFAOYSA-N

1140965-47-4

E7766 (diammonium salt) (4 suppliers)

2242635-03-4

E7766 (disodium) (2 suppliers)

2242636-28-6

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